Tesamorelin – 5mg

1. HIV-Associated Lipodystrophy and Visceral Fat Reduction
   Tesamorelin remains the only FDA-approved peptide therapy for HIV-associated lipodystrophy, a condition marked by dysfunctional fat deposition. Clinical studies show that Tesamorelin can reduce visceral adiposity by nearly 20%, a result that is approximately 4x more effective than other available interventions. Its role in modifying fat distribution without altering subcutaneous fat has made it a focal point for studies involving metabolic dysfunction.
2. Cardiovascular Risk and Inflammation
   Research indicates that Tesamorelin not only reduces visceral fat, but also lowers triglycerides, total cholesterol, and non-HDL-C levels in HIV-positive individuals. Visceral adiposity has been strongly correlated with systemic inflammation, which contributes to increased cardiovascular disease risk. By reducing ectopic fat deposits and their inflammatory signaling, Tesamorelin is being evaluated as a cardiometabolic modulator.
3. Growth Hormone Deficiency in HIV Patients
   A growing body of research links long-term antiretroviral therapy (HAART) to pituitary dysfunction and growth hormone deficiency. Approximately one-third of HIV-positive patients on HAART exhibit suppressed GH production. Tesamorelin’s ability to restore endogenous GH levels—without exogenous GH administration—positions it as a valuable candidate for endocrine recovery research in this population.
4. Peripheral Nerve Repair
   Tesamorelin is being explored as a neuroregenerative agent, particularly for peripheral nerve damage resulting from trauma, surgery, or metabolic dysfunction. Animal studies suggest that growth hormone analogues like Tesamorelin may promote axon regeneration, remyelination, and functional recovery in injured nerves.
5. Mild Cognitive Impairment (MCI) and Brain Aging
   As growth hormone and IGF-1 have been implicated in cognitive health, Tesamorelin is under study for its potential role in slowing the progression of MCI, often a precursor to dementia. Early-stage research is evaluating how GH analogues influence neuroplasticity, synaptic signaling, and neuroinflammation in aging populations.

• Unreconstituted: Store at -20°C in a sealed, light-protected container
• Reconstituted: Use within recommended timeframes at 2–8°C
• Reconstitute using bacteriostatic water or laboratory-grade diluents. Protect from light and avoid repeated freeze-thaw cycles.

This compound is intended strictly for laboratory research, in vitro experimentation, and preclinical studies. Tesamorelin is not approved for human or veterinary use and must be handled by qualified personnel in controlled research settings.

All True Science Peptides products undergo third-party verification via HPLC and Mass Spectrometry and are accompanied by batch-specific Certificates of Analysis.