Semaglutide – 10mg

1. Appetite Regulation and Gastric Emptying
   Semaglutide’s most widely studied application is in the area of appetite suppression and satiety signaling. By slowing gastric emptying and reducing intestinal motility, GLP-1 receptor agonists help decrease food intake and support modeling of caloric restriction and obesity resistance.
   
   In rodent and primate studies, Semaglutide administration led to marked reductions in feeding behavior, accompanied by measurable decreases in total caloric intake and weight gain.
   
2. Insulin Secretion and Glucose Homeostasis
   As a glucose-dependent insulinotropic agent, Semaglutide supports research in type 2 diabetes and pancreatic beta-cell preservation. It enhances insulin secretion only when blood glucose is elevated, reducing the risk of hypoglycemia while still offering robust glycemic control in experimental models.
   
   Semaglutide also inhibits glucagon secretion, a key mechanism for regulating postprandial glucose spikes.
   
3. Cardiovascular and Hepatic Models
   Emerging studies have highlighted the potential of Semaglutide to improve cardiovascular markers, including:
   
   non-alcoholic steatohepatitis (NASH) and fatty liver disease research.
   
4. Neuroprotective Effects and Alzheimer’s Models
   Recent research suggests Semaglutide may offer neurotrophic and anti-amyloid effects, making it a growing focus in Alzheimer’s disease and cognitive decline models. It appears to support brain health through:

• Unreconstituted: Store at -20°C in a sealed, light-protected container
• Reconstituted: Use within recommended timeframes at 2–8°C
• Reconstitute with bacteriostatic water or lab-approved diluent per your research protocol. Avoid exposure to direct light and moisture.

This compound is intended strictly for scientific research and laboratory experimentation. Semaglutide is not approved for human or veterinary use, and must be handled exclusively by trained personnel in compliant research environments.

All True Science Peptides compounds are independently verified via HPLC and Mass Spectrometry and are shipped with batch-specific Certificates of Analysis.