Ipamorelin – 5mg

1. Receptor Selectivity and Mechanistic Specificity
   Ipamorelin’s GHS-R1a activation mimics the natural pulsatile release of GH while minimizing off-target hormonal effects. This has made it a model peptide in investigations aiming to enhance GH secretion without interfering with other endocrine pathways.
2. Bone Density and Skeletal Support
   Animal models show that Ipamorelin may significantly prevent and reverse corticosteroid-induced bone loss. In glucocorticoid-exposed rats, Ipamorelin was associated with a 4-fold increase in bone formation and improved bone mineral density. It is being studied as a potential adjunct in therapies targeting osteoporosis and glucocorticoid-related skeletal degeneration.
3. Muscular Integrity and Anti-Catabolic Properties
   Research in rats demonstrates that Ipamorelin attenuates muscle wasting, improves nitrogen balance, and helps to preserve lean tissue mass during periods of elevated catabolic activity—particularly in conjunction with glucocorticoid use.
4. Glucose Homeostasis and Pancreatic Studies
   Ipamorelin has been observed to potentiate insulin release in diabetic rodent models. While indirect, the effect is believed to stem from increased calcium channel signaling in pancreatic islet cells. This pathway offers insight into potential new strategies for glycemic regulation and diabetes-related research.
5. GI Motility and Post-Operative Recovery
   Ipamorelin has been studied for its use in reducing post-operative ileus (POI)—a common complication after abdominal surgeries. Preclinical data indicate that the peptide may restore gastrointestinal motility, shorten recovery time, and potentially improve nutritional uptake in postoperative care models.

• Unreconstituted: Store at -20°C in a sealed, light-protected container
• Reconstitute using bacteriostatic water or laboratory-approved diluents. Protect from light and moisture; avoid repeated freeze-thaw cycles.
• Reconstituted: Use within recommended timeframes at 2–8°C

This compound is intended strictly for scientific research, in vitro experimentation, and preclinical modeling. Ipamorelin is not approved for human or veterinary use and must be handled only by qualified laboratory professionals.

All True Science Peptides products undergo third-party HPLC and Mass Spectrometry validation, with batch-specific Certificates of Analysis provided.